xqtl_single_snp_mr( exposure_gene = NULL, outcome_trait = NULL, snp = NULL, qtl_type = c("eQTL", "pQTL"), pval_threshold = 1e-05, mode = c("table", "raw") )
| exposure_gene | Name of the exposure gene |
|---|---|
| outcome_trait | Name of the outcome trait |
| snp | SNP rsid |
| qtl_type | "eQTL" or "pQTL" |
| pval_threshold | P-value threshold |
| mode | If |
Data from GEET /xqtl/single-snp-mr
xqtl_single_snp_mr(outcome_trait = "Coronary heart disease")#> # A tibble: 489 x 8 #> gene.ensembl_id gene.name gwas.id gwas.trait r.beta r.se r.p r.rsid #> <chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> #> 1 ENSG00000147889 CDKN2A ieu-a-7 Coronary hea… -2.95 0.202 0. rs702… #> 2 ENSG00000173207 CKS1B ieu-a-7 Coronary hea… 0.769 0.0943 3.34e-16 rs140… #> 3 ENSG00000134222 PSRC1 ieu-a-7 Coronary hea… -0.231 0.0297 7.40e-15 rs497… #> 4 ENSG00000140403 DNAJA4 ieu-a-7 Coronary hea… -1.37 0.193 1.12e-12 rs290… #> 5 ENSG00000197520 FAM177B ieu-a-7 Coronary hea… 0.278 0.0417 2.84e-11 rs340… #> 6 ENSG00000147883 CDKN2B ieu-a-7 Coronary hea… -1.20 0.182 4.09e-11 rs218… #> 7 ENSG00000160179 ABCG1 ieu-a-7 Coronary hea… -1.21 0.186 8.17e-11 rs7412 #> 8 ENSG00000150687 PRSS23 ieu-a-7 Coronary hea… -1.11 0.174 1.93e-10 rs110… #> 9 ENSG00000134198 TSPAN2 ieu-a-7 Coronary hea… -1.13 0.178 1.93e-10 rs110… #> 10 ENSG00000171988 JMJD1C ieu-a-7 Coronary hea… -1.00 0.157 1.93e-10 rs110… #> # … with 479 more rows