The default multiplicative random effects IVW estimate. The standard error is corrected for under dispersion Use the mr_ivw_mre function for estimates that don't correct for under dispersion.

mr_uwr(b_exp, b_out, se_exp, se_out, parameters = default_parameters())

Arguments

b_exp

Vector of genetic effects on exposure.

b_out

Vector of genetic effects on outcome.

se_exp

Standard errors of genetic effects on exposure.

se_out

Standard errors of genetic effects on outcome.

parameters

List of parameters. The default is default_parameters().

Value

List with the following elements:

b

MR estimate

se

Standard error

pval

p-value

Q, Q_df, Q_pval

Heterogeneity stats