Maximum likelihood MR method
Usage
mr_two_sample_ml(b_exp, b_out, se_exp, se_out, parameters)
Arguments
- b_exp
Vector of genetic effects on exposure.
- b_out
Vector of genetic effects on outcome.
- se_exp
Standard errors of genetic effects on exposure.
- se_out
Standard errors of genetic effects on outcome.
- parameters
List of parameters.
Value
List with the following elements:
- b
causal effect estimate
- se
standard error
- pval
p-value
- Q, Q_df, Q_pval
Heterogeneity stats