MR simple mode estimator

mr_simple_mode(b_exp, b_out, se_exp, se_out, parameters = default_parameters())

Arguments

b_exp

Vector of genetic effects on exposure

b_out

Vector of genetic effects on outcome

se_exp

Standard errors of genetic effects on exposure

se_out

Standard errors of genetic effects on outcome

parameters

List containing phi - Bandwidth parameter, and nboot - number of bootstraps to calculate SE. default_parameters() sets list(phi=1, nboot=1000).

Value

List with the following elements:

b

MR estimate

se

Standard error

pval

p-value