Perform 2 sample IV using fixed effects meta analysis and delta method for standard errors — mr_meta_fixed • TwoSampleMR

Perform 2 sample IV using fixed effects meta analysis and delta method for standard errors

Usage

mr_meta_fixed(b_exp, b_out, se_exp, se_out, parameters)

Arguments

b_exp: Vector of genetic effects on exposure.
b_out: Vector of genetic effects on outcome.
se_exp: Standard errors of genetic effects on exposure.
se_out: Standard errors of genetic effects on outcome.
parameters: List of parameters.

Value

List with the following elements:

b: causal effect estimate
se: standard error
pval: p-value
Q, Q_df, Q_pval: Heterogeneity stats