Imported here to help estimate sample overlap between studies
ldsc_h2(id, ancestry = "infer", snpinfo = NULL, splitsize = 20000)
ID to analyse
ancestry of traits 1 and 2 (AFR, AMR, EAS, EUR, SAS) or 'infer' (default) in which case it will try to guess based on allele frequencies
Output from ieugwasr::afl2_list("hapmap3"), or NULL for it to be done automatically
How many SNPs to extract at one time. Default=20000
Bulik-Sullivan,B.K. et al. (2015) An atlas of genetic correlations across human diseases and traits. Nat. Genet. 47, 1236–1241.
Guo,B. and Wu,B. (2018) Principal component based adaptive association test of multiple traits using GWAS summary statistics. bioRxiv 269597; doi: 10.1101/269597
Gua,B. and Wu,B. (2019) Integrate multiple traits to detect novel trait-gene association using GWAS summary data with an adaptive test approach. Bioinformatics. 2019 Jul 1;35(13):2251-2257. doi: 10.1093/bioinformatics/bty961.