TwoSampleMR: Two Sample MR Functions and Interface to MR Base Database

A package for performing Mendelian randomization using GWAS summary data. It uses the IEU GWAS database https://gwas.mrcieu.ac.uk/ to automatically obtain data, and a wide range of methods to run the analysis. You can use the MR-Base web app https://www.mrbase.org/ to try out a limited range of the functionality in this package, but for any serious work we strongly recommend using this R package.

See also

Useful links:

• https://github.com/MRCIEU/TwoSampleMR

• https://mrcieu.github.io/TwoSampleMR/

• Report bugs at https://github.com/MRCIEU/TwoSampleMR/issues/

Author

Maintainer: Gibran Hemani g.hemani@bristol.ac.uk (ORCID)

Authors:

• Philip Haycock philip.haycock@bristol.ac.uk (ORCID)

• Jie Zheng Jie.Zheng@bristol.ac.uk (ORCID)

• Tom Gaunt Tom.Gaunt@bristol.ac.uk (ORCID)

• Ben Elsworth Ben.Elsworth@bristol.ac.uk (ORCID)

• Tom Palmer tom.palmer@bristol.ac.uk (ORCID)